What are the uses of Dextran series?

Dextran series can be used in vaccines, eye drops or similar solutions, protein stability, lyophilization, cryo-Protectant, organ preservation, oral application, blood cell separation, blood volume expander and so on. As Dextran GMP manufacturer, the specific applications of our Dextran series products are as follows:

Uses

Description

Our products

Vaccines

Dextran series can be part of vaccines as a carrier, a back-bone and/or as a stabilizer of the antigen or other subunits.

Dextran 1

Dextran 10

Dextran 40

Dextran 70

Eye Drops or Similar Solutions

Dextran series are often used in eye drops or similar solution for ophthalmic application. They can be used as the active ingredient in eye drops due to its lubricating nature or as tear-replacement. This application is used to relieve dry, irritated eyes.

Dextran 40

Dextran 70

Protein stability

Dextran series are known to benefit on structural stability of freeze-dried products, protein stability and the recovery of enzyme activity after freeze-drying.

Dextran 1

Dextran 5

Dextran 10

Dextran 40

Dextran 70

Lyophilization

Dextran series are used as Excipient in Lyophilization (freeze-drying).

Dextran 1

Dextran 10

Dextran 40

Dextran 70

Cryo-Protectant

Dextran series can be used as a cryo-protectant in combination with DSMO, glycerol etc. They can be used to cryo-preserve cell lines, stem cell preparations and biological samples in general.

Dextran 10

Dextran 40

Dextran 70

Organ Preservation

Dextran series is widely accepted as solution for storing and preparing organs for transplantation.

Dextran 1

Dextran 40

Dextran 70

Oral Application

Dextran series have a wide use in oral pharmaceuticals. They are applied for solidity and viscosity adjustment during substance processing.

Dextran 1

Dextran 5

Dextran 10

Dextran 40

Dextran 70

Blood Cell Separation

Dextran can be applied in the reversible aggregation of human red blood cells, yet the mechanism governing the process are still being explored. The process is useful for separation of red blood cells from other cells and components of the blood.

Dextran 70

Blood Volume Expander

Intravenous solutions with dextran function have the effect of volume expanders and parenteral nutrition. Such a solution provides an osmotically neutral fluid that once in the body is digested by cells into glucose and free water. It is occasionally used to replace lost blood in emergency situations when replacement blood is not available.

Dextran 1

Dextran 40

Dextran 70