Question 1: Who needs to supplement with L-alanyl-L-glutamine Injection?
Answer: As long as the self-synthesized glutamine cannot meet the needs of the bodyfor patients(including but not limited to severe burns, tumor radiotherapy and chemotherapy, inflammatory bowel disease, AIDS, etc.), supplementation with L-alanyl-L-glutamine Injection can improve nitrogen balance, maintain intestinal barrier and immune function, and then improve the clinical outcomes of patients.
Question 2: Is L-alanyl-L-glutamine Injection supplemented by parenteralnutritionor enteralnutrition?
Answer: Both enteral and parenteral are acceptable. For patients undergoing enteralnutrition or parenteralnutritiontherapy,it can also be supplemented intravenously.
Question 3: What is the appropriate clinical dose of L-alanyl-L-glutamine Injection and its proportion in total amino acids?
Answer: The pharmacological dose should be 0.3-0.5g (kg.d). It should be mixed with all-in-one parenteral nutrition solution, amino acid or glucose solution. The proportion of amino acids in parenteral nutrition should be kept at 20% to 30% according to the metabolism of the disease.
Question 4: How safe is L-alanyl-L-glutamine Injectionin clinical application ?
Answer: The safety of the 0.5g/(kg.d)dosehas been fully demonstrated. It should be used with caution in patients with severe liver and kidney function damage.It is not recommended for patients with severe liver and kidney failure caused by sepsis or other reasons.