Introduction of L-Alanyl-L-glutamine

L-Alanyl-L-glutamine belongs to class of drugs called amino acids, and that is a dipeptide molecule, consisting of L-glutamine and L-alanine, two amino acids. It works by inhibiting the muscle break down and increases the synthesis of muscle proteins and also it improves electrolyte and water absorption in the intestines and increases the body's natural defense mechanism.It is used in the treatment of Short term fluid replacement after trauma.


L-Alanyl-L-glutamine is sometimes supplemented before prolonged physical exercise to enhance electrolyte absorption and improve endurance.


Preliminary rodent evidence suggestsL-Alanyl-L-glutamine is more effective at increasing muscular glutamine content after supplementation thanglutamine itself. This is because glutamine is absorbed by the liver and intestines after supplementation. SinceL-Alanyl-L-glutamine is a dipeptide molecule, it contains more than one amino acid for the intestines to absorb, allowing glutamine to reach the muscles.


L-Alanyl-L-glutamine is more stable and far more water soluble than regular L-glutamine. Moreover, dipeptides are usually absorbed faster than free amino acids, due to the intact and efficient dipeptide transport carrier they employ.